3d Cell Culture Using Monodisperse Peptide Hydrogel Beads

نویسندگان

  • Yukiko Tsuda
  • Yuya Morimoto
  • Shoji Takeuchi
چکیده

We describe a three-dimensional (3D) cell culture system using monodisperse peptide hydrogel beads. We utilized a self-assembling peptide hydrogel to provide cells in vivo-like microenvironment. We succeeded in encapsulating endothelial cells within the hydrogels by using a 3D microfluidic axisymmetric flow-focusing device (AFFD), and showed the encapsulated endothelial cells were viable and were able to migrate within the gels.

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تاریخ انتشار 2008